Structural formula
| Business number | 013S |
|---|---|
| Molecular formula | C19H24N2 |
| Molecular weight | 280.41 |
| label |
Mipramine, 10,11-Dihydro-5-(3-(dimethylamino)propyl)-5H-dibenz[b,f]azepine |
Numbering system
CAS number:50-49-7
MDL number:None
EINECS number:200-042-1
RTECS number:None
BRN number:None
PubChem ID:None
Physical property data
1. Properties: Its hydrochloride is commonly used. It is a white crystalline powder
2. Density (g/mL, 25/4?): Undetermined
3. Relative vapor density (g/mL, air=1): Undetermined
4. Melting point (ºC): Undetermined
5. Boiling point (ºC, normal pressure): Undetermined
6. Boiling point (ºC, 5.2 kPa): Not determined
7. Refractive index: Not determined
8. Flash point (ºC): Not determined
9. Specific rotation ( º): Not determined
10. Autoignition point or ignition temperature (ºC): Not determined
11. Vapor pressure (kPa, 25 ºC): Not determined
12. Saturated vapor pressure (kPa, 60 ºC): Undetermined
13. Heat of combustion (KJ/mol): Undetermined
14. Critical temperature (ºC) : Undetermined
15. Critical pressure (KPa): Undetermined
16. Log value of oil-water (octanol/water) partition coefficient: Undetermined
17. Explosion upper limit (%, V/V): Undetermined
18. Explosion lower limit (%, V/V): Undetermined
19. Solubility: Easily soluble In water, it gradually turns yellow-red when exposed to water
Toxicological data
None
Ecological data
None
Molecular structure data
1. Molar refractive index: 88.92
2. Molar volume (cm3/mol): 269.2
3. Isotonic specific volume (90.2K ): 677.5
4. Surface tension (dyne/cm): 40.1
5. Polarizability (10-24cm3): 35.25
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): None
2. Number of hydrogen bond donors: 0
3. Number of hydrogen bond acceptors: 2
4. Number of rotatable chemical bonds: 4
5. Number of tautomers: none
6. Topological molecule polar surface area 6.5
7. Number of heavy atoms: 21
8. Surface charge: 0
9. Complexity: 291
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. TotalNumber of key units: 1
Properties and stability
None
Storage method
This product should be sealed and stored in a dry place away from light.
Synthesis method
It is produced by condensing and reducing o-nitrotoluene to obtain 2,2?-aminobibenzyl and condensing with 1-chloro-3-dimethylaminopropane to form a salt.
Purpose
It has a strong antidepressant effect, but its stimulating effect is not obvious and its sedative effect is weak. It is almost ineffective or has poor curative effect on the depressive state associated with schizophrenia. It can also be used for enuresis in children.
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