N-Methylmorpholine

N-Methylmorpholine is an organic base of intermediate strength. Its main use is as the starting material for preparing N-methylmorpholine N-oxide.

Properties
Appearance & Physical State: clear liquid
Density: 0.92
Melting Point: -66.1ºC
Boiling Point: 115-116ºC (750 mmHg)
Flash Point: 13ºC
Refractive Index: 1.4339-1.4359
Water Solubility: >500 g/L (20 ºC)
Stability: Stable at room temperature in closed containers under normal storage and handling conditions.
Storage Condition: Store at RT.
Vapor Pressure: 18 mm Hg ( 20 °C)
Vapor Density: >1 (vs air)
Safety Info
RTECS: QE5775000
Hazard Class: 3
Safety Statements: S16-S25-S36/37/39-S45
HS Code: 2934999090
Packing Group: II
WGK Germany: 1
RIDADR: UN 2535
Risk Statements: R11; R20/21/22; R34
Hazard Codes: C

Morpholine

Morpholine is an organic chemical compound having the chemical formula O(CH2CH2)2NH. This heterocycle features both amine and ether functional groups. Because of the amine, morpholine is a base; its conjugate acid is called morpholinium. For example, treating morpholine with hydrochloric acid makes the salt morpholinium chloride.

Properties
Appearance & Physical State: aqueous solution with a fishlike odor
Density: 0.994
Melting Point: -5ºC
Freezing Point: -4.9?
Boiling Point: 129ºC
Flash Point: 38ºC
Refractive Index: 1.453-1.455
Water Solubility: MISCIBLE
Stability: Stable. Flammable. Incompatible with strong oxidizing agents, strong acids, acid chlorides, acid anhydrides. Hygroscopic.
Storage Condition: Store at R.T.
Vapor Pressure: 31 mm Hg ( 38 °C)
Vapor Density: 3 (vs air)
Safety Info
RTECS: QD6475000
Hazard Class: 8
Safety Statements: S23-S36-S45
HS Code: 2934999090
Packing Group: I
WGK Germany: 3
RIDADR: UN 2054/1760
Risk Statements: R10; R20/21/22; R34
Hazard Codes: C

DGA

2-(2-Aminoethoxy)ethanol is a widely used reactant that has been used in the preparation of TD-4306 as long-acting ?2-agonist for asthma and COPD therapy.

Properties
Appearance & Physical State: clear to very slight yellow liquid
Density: 1.05
Melting Point: -12.5ºC
Boiling Point: 218-224ºC
Flash Point: 127ºC
Refractive Index: 1.4585-1.4605
Water Solubility: miscible
Stability: Stable. Incompatible with acids, strong oxidizing agents. Reacts with carbon dioxide.
Storage Condition: Keep away from heat, sparks, and flame. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store in metal containers.

 

Safety Info
RTECS: KJ6125000
Hazard Class: 8
Safety Statements: S24/25-S26
HS Code: 29221980
Packing Group: III
WGK Germany: 1
RIDADR: UN 3055/1760
Risk Statements: R21; R34
Hazard Codes: C