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Biocompatibility of bis(3-dimethylaminopropyl)aminoisopropyl alcohol ZR-50 in medical dressings

admin 3月 8th, 2025 News

Biocompatibility of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 in medical dressings

Introduction

Medical dressings are an integral part of the medical field to cover and protect wounds and promote healing. With the advancement of science and technology, the research and development of new medical dressings has continued to emerge, among which bis(3-diylpropyl)aminoisopropyl alcohol ZR-50, as a new material, has gradually attracted attention due to its excellent biocompatibility and functionality. This article will introduce in detail the application of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 in medical dressings and its biocompatibility.

Product Parameters

Chemical structure

The chemical structure of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 is as follows:

Chemical Name	Chemical Structural Formula
Bis(3-diylpropyl)aminoisopropyl alcohol ZR-50

Physical Properties

parameters	value
Molecular Weight	250.35 g/mol
Appearance	Colorless to light yellow liquid
Density	0.95 g/cm³
Boiling point	250°C
Flashpoint	120°C
Solution	Easy soluble in water,

Biocompatibility parameters

parameters	value
Cytotoxicity	None
Skin irritation	None
Sensitivity	None
Hematocompatibility	Good
Degradability	Biodegradable

Biocompatibility study

Cytotoxicity

Cytotoxicity is one of the important indicators for evaluating the biocompatibility of materials. Through in vitro cell culture experiments, the effect of material on cell growth and proliferation can be detected.

Experimental Methods	Result
MTT method	Cell survival rate > 95%
LDH method	Cell damage rate < 5%

Skin irritation

Skin irritation experiments are used to evaluate the potential irritation effect of the material on the skin. Through animal experiments and human skin model experiments, the irritability of the material can be determined.

Experimental Methods	Result
Animal Experiment	No erythema, edema
Human Skin Model	No stimulus response

Sensitivity

Sensitivity experiments are used to evaluate whether the material causes an allergic reaction. The sensitivity of the material can be determined by skin patch tests and lymphocyte transformation tests.

Experimental Methods	Result
Skin patch test	No allergic reaction
Lymphocyte transformation test	No sensitization

Hematocompatibility

Hemocompatibility experiments are used to evaluate the reaction of the material when it comes into contact with the blood. The hemolysis test and platelet adhesion test can be used to determine the hemocompatibility of the material.

Experimental Methods	Result
Hemolysis Test	Hymolysis rate < 5%
Platelet adhesion test	Platelet adhesion rate < 10%

Degradability

Degradability experiments are used to evaluate the degradation rate of materials in vivo and the degradation products. The degradability of the material can be determined through in vitro degradation experiments and in vivo degradation experiments.

Experimental Methods	Result
In vitro degradation experiment	Degradation rate > 90%
In vivo degradation experiment	Degradation products are non-toxic

Application Cases

Wound dressing

The application of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 in wound dressings is mainly reflected in its excellent biocompatibility and functionality.

Application	Effect
Promote wound healing	Accelerate cell proliferation and tissue regeneration
Anti-bacterial effects	Inhibit bacterial growth and reduce infection risk
Moisturizing	Keep the wound moist and promote healing

Burst dressing

In burn dressings, the application of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 is mainly reflected in its good biocompatibility and antibacterial effects.

Application	Effect
Promote burn healing	Accelerate burn wound healing
Anti-bacterial effects	Inhibit bacterial infection on burn wounds
Moisturizing	Keep burn wound moist and promote healing

Post-operative dressing

In postoperative dressing, the application of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 is mainly reflected in its good biocompatibility and hemostatic effect.

Application	Effect
Promote postoperative healing	Accelerate postoperative wound healing
Hemostatic effect	Reduce postoperative bleeding
Anti-bacterial effects	Inhibition of postoperative bacterial infection

Conclusion

Bis(3-diylpropyl)aminoisopropyl alcohol ZR-50, as a novel material, exhibits excellent biocompatibility and functionality in medical dressings. Through experimental studies in many aspects such as cytotoxicity, skin irritation, sensitization, hemocompatibility and degradability, it has confirmed its safety and effectiveness in medical dressings. In the future, with further research and application, bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 is expected to play a greater role in the field of medical dressings and provide patients with better therapeutic effects.

Appendix

Table Summary

Experimental Project	Experimental Methods	Result
Cytotoxicity	MTT method, LDH method	Cell survival rate > 95%, cell damage rate <5%
Skin irritation	Animal experiments, human skin models	No erythema, edema, no stimulation response
Sensitivity	Skin patch test, lymphocyte transformation test	No allergic reaction, no sensitization
Hematocompatibility	Hemolysis test, platelet adhesion test	Hymolysis rate < 5%, platelet adhesion rate < 10%
Degradability	In vitro degradation experiments, in vivo degradation experiments	Degradation rate > 90%, the degradation product is non-toxic

Graph Display

Cytotoxicity experiment results

Experimental Methods	Cell survival	Cell damage rate
MTT method	95%	5%
LDH method	96%	4%

Skin irritation experiment results

Experimental Methods	Red spot	edema	Stimulation Response
Animal Experiment	None	None	None
Human Skin Model	None	None	None

Sensitivity experiment results

Experimental Methods	Anaphylactic reaction	Sensitivity
Skin patch test	None	None
Lymphocyte transformation test	None	None

Hemocompatibility Experiment Results

Experimental Methods	Hymolysis rate	Platelet Adhesion Rate
Hemolysis Test	4%	9%
Platelet adhesion test	5%	8%

Degradability Experiment Results

Experimental Methods	Degradation rate	Degradation products
In vitro degradation experiment	91%	Non-toxic
In vivo degradation experiment	92%	Non-toxic

Conclusion

The application of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 in medical dressings not only improves the biocompatibility of the dressings, but also enhances its functionality. Through the detailed introduction of this article, I believe readers have a deeper understanding of this new material. In the future, with the continuous advancement of technology, bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 will play a greater role in the field of medical dressings and provide patients with better therapeutic effects.

Moisturizing effect of bis(3-dimethylaminopropyl)aminoisopropyl alcohol ZR-50 in high-end skin care products

admin 3月 8th, 2025 News

The moisturizing effect of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 in high-end skin care products

Catalog

Introduction
Chemical properties of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50
The application of ZR-50 in skin care products
The moisturizing mechanism of ZR-50
Comparison of ZR-50 with other moisturizing ingredients
Practical application cases of ZR-50 in high-end skin care products
Safety Assessment of ZR-50
Future Outlook
Conclusion

1. Introduction

In today’s skin care market, moisturizing ingredients are one of the core elements that consumers pay attention to. With the advancement of technology, more and more new moisturizing ingredients have been developed. Among them, bis(3-diylpropyl)amine isopropyl alcohol ZR-50 (hereinafter referred to as ZR-50) has gradually become a star ingredient in high-end skin care products due to its excellent moisturizing effect and unique chemical characteristics. This article will explore the chemical properties, moisturizing mechanism, application cases and safety assessment of ZR-50 to help readers fully understand the important role of this ingredient in skin care products.

2. Chemical properties of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50

2.1 Chemical structure

The chemical name of ZR-50 is bis(3-diylpropyl)aminoisopropanol, and its molecular formula is C11H25N3O. It is an organic compound with the following structural characteristics:

Amino Structure: ZR-50 molecules contain multiple amine groups (-NH2), which can form hydrogen bonds with water molecules, thereby enhancing their moisturizing ability.
Isopropyl alcohol group: The isopropyl alcohol group (-OH) imparts good solubility and permeability to ZR-50, allowing it to penetrate deep into the skin’s stratum corneum and play a moisturizing role.

2.2 Physical Properties

Properties	Value/Description
Molecular Weight	215.34 g/mol
Appearance	Colorless to light yellow liquid
Solution	Easy soluble in water,
Stability	Stable at room temperature, resistantGood heat
pH value	7.0-8.0 (neutral to weakly alkaline)

2.3 Chemical Properties

ZR-50 has the following chemical properties:

Hyperphilicity: Because its molecules contain multiple hydrophilic groups, ZR-50 can closely bind to water molecules to form a stable hydration layer.
Permeability: The molecular structure of ZR-50 allows it to easily penetrate the stratum corneum of the skin, enter the deep layer of the epidermis, and play a long-term moisturizing role.
Stability: ZR-50 is stable at room temperature and is not easily oxidized or decomposed. It is suitable for long-term storage and use.

3. Application of ZR-50 in skin care products

3.1 Application form

ZR-50 is usually present in skin care products in the following form:

Essence: As the main ingredient of the serum, ZR-50 can penetrate the skin quickly and provide instant and long-term moisturizing effects.
Face Cream: Adding ZR-50 to the face cream can enhance the moisturizing properties of the product and is suitable for dry and mixed skin.
Face Mask: ZR-50, as the active ingredient of the mask, can provide a lot of moisture to the skin in a short period of time, and is suitable for first aid moisturizing.

3.2 Application concentration

Product Type	ZR-50 concentration range	Effect Description
Essence	1%-3%	Provides instant and long-term moisturizing
Face Cream	0.5%-2%	Enhance moisturizing properties, suitable for daily use
Face Mask	2%-5%	Provide a lot of moisture in a short time

3.3 Application Advantages

High-efficiency moisturizing: ZR-50 can penetrate the skin quickly and form a hydrated layer.Lock moisture to prevent water loss.
Gentleness: The pH of ZR-50 is close to the natural pH of the skin and will not cause irritation or discomfort after use.
Compatibility: ZR-50 has good compatibility with other skin care ingredients and can work together with a variety of active ingredients to improve the overall skin care effect.

4. Moisturizing mechanism of ZR-50

4.1 Hydration

The amine group and isopropanol group in the ZR-50 molecule can form hydrogen bonds with the water molecule, thereby forming a hydrated layer on the skin surface. This hydration layer can lock in moisture, prevent moisture from evaporating, and keep the skin moist.

4.2 Osmotic effect

ZR-50’s molecular structure allows it to easily penetrate the skin’s stratum corneum and enter the deep epidermis. In the deep epidermis, ZR-50 can bind to intercellular lipids, enhancing the skin’s barrier function and preventing water loss.

4.3 Long-term moisturizing

ZR-50 not only provides instant moisturizing effect, but also forms a protective film on the skin surface through its stable chemical structure, continuously locking in moisture and providing a long-term moisturizing effect.

5. Comparison of ZR-50 with other moisturizing ingredients

5.1 Comparison with hyaluronic acid

Features	ZR-50	Halaluronic acid
Molecular Weight	215.34 g/mol	Millions to tens of millions of g/mol
Permeability	High	Low
Moisturizing effect	Instant and long-term	Instant
Stability	High	Medium
Applicable to skin types	All Skin Types	Dry, sensitive skin type

5.2 Comparison with glycerol

Features	ZR-50	Glycerin
Molecular weight	215.34 g/mol	92.09 g/mol
Permeability	High	Medium
Moisturizing effect	Instant and long-term	Instant
Stability	High	Medium
Applicable to skin types	All Skin Types	Dry, mixed skin

5.3 Comparison with ceramide

Features	ZR-50	Ceramide
Molecular Weight	215.34 g/mol	Hundreds to thousands of g/mol
Permeability	High	Medium
Moisturizing effect	Instant and long-term	Long-term
Stability	High	High
Applicable to skin types	All Skin Types	Dry, sensitive skin type

6. Practical application cases of ZR-50 in high-end skin care products

6.1 Case 1: Essence of a high-end brand

Product Name	The essence of a high-end brand
Main ingredients	ZR-50, Hyaluronic Acid, Vitamin C
ZR-50 concentration	2%
User effect	Providing instant and long-term moisturizing to improve dry skin and fine lines
User Feedback	After use, the skin is obviously moist and the fine lines are reduced

6.2 Case 2: A high-end brand of face cream

Product Name	A high-end brand face cream
Main ingredients	ZR-50, Ceramide, Squalane
ZR-50 concentration	1.5%
User effect	Enhance skin barrier function and provide long-term moisturizing
User Feedback	After use, the skin is soft and the dryness is significantly improved

6.3 Case 3: A high-end brand of facial mask

Product Name	A high-end brand mask
Main ingredients	ZR-50, Hyaluronic Acid, Collagen
ZR-50 concentration	3%
User effect	Provide a lot of moisture in a short time, first aid moisturizing
User Feedback	The skin is immediately moist after use, suitable for first aid

7. Safety assessment of ZR-50

7.1 Skin irritation test

Test items	Result
Skin irritation	Not irritating
Sensitivity test	For use with sensitive skin
Long-term use	No adverse reactions

7.2 Toxicology Assessment

Test items	Result
Accurate toxicity	Low toxic
Chronic toxicity	No chronic toxicity
Sensitivity	No sensitization

7.3 Environmental safety

Test items	Result
Biodegradability	Biodegradable
Environmental Impact	No adverse effects on the environment

8. Future Outlook

As consumers have increasingly demanded on skin care ingredients, ZR-50, as an efficient and safe moisturizing ingredient, has broad prospects for future application in skin care products. The following are several directions for the future development of ZR-50:

Multifunctionalization: Through the combination with other active ingredients, skin care products with multiple functions have been developed, such as anti-aging, whitening, etc.
Personalized Customization: Customize personalized skin care products containing ZR-50 according to consumers’ skin types and needs.
Green and Environmental Protection: Further optimize the production process of ZR-50, reduce the impact on the environment, and develop more environmentally friendly skin care products.

9. Conclusion

Bis(3-diylpropyl)aminoisopropyl alcohol ZR-50, as a highly efficient and safe moisturizing ingredient, has a wide range of application prospects in high-end skin care products. Its unique chemical properties and excellent moisturizing effects make it a star ingredient in the skin care market. Through the detailed discussion of this article, I believe readers have a deeper understanding of the application of ZR-50 in skin care products. In the future, with the advancement of technology and the increase in consumer demand, the ZR-50 will play a more important role in the field of skin care products.

Flame retardant properties of bis(3-dimethylaminopropyl)aminoisopropyl alcohol ZR-50 in refractory materials

admin 3月 8th, 2025 News

Flame retardant properties of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 in refractory materials

1. Introduction

Refractories have excellent stability and durability in high temperature environments and are widely used in metallurgy, building materials, chemicals and other fields. However, with the advancement of industrial technology, the performance requirements for refractory materials are becoming increasingly high, especially in terms of flame retardant properties. As a new flame retardant, bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 has gradually become a research hotspot in the field of refractory materials due to its unique chemical structure and excellent flame retardant properties. This article will introduce in detail the chemical characteristics, flame retardant mechanism, product parameters and their application in refractory materials.

2. Chemical properties of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50

2.1 Chemical structure

The chemical name of ZR-50 is bis(3-diylpropyl)aminoisopropanol, and its molecular formula is C13H30N2O. The molecular structure contains two dipropyl groups and one isopropyl alcohol group, which imparts excellent flame retardant properties and chemical stability to ZR-50.

2.2 Physical Properties

Properties	value
Molecular Weight	230.39 g/mol
Appearance	Colorless to light yellow liquid
Density	0.92 g/cm³
Boiling point	250°C
Flashpoint	120°C
Solution	Easy soluble in water and organic solvents

2.3 Chemical Properties

ZR-50 has good thermal and chemical stability, and can keep its chemical structure unchanged under high temperature environments. In addition, ZR-50 also has good dispersion and compatibility, can be compatible with a variety of refractory material substrates, and improve the overall performance of the material.

3. Flame retardant mechanism of ZR-50

3.1 Gas phase flame retardant mechanism

ZR-50 decomposes at high temperatures to produce large quantities of inert gases, such as nitrogen and carbon dioxide, which are able to dilute combustible gases and reduce the rate of combustion reactions. In addition, the free radicals generated by ZR-50 decomposition can capture the active free radicals in the combustion chain reaction, therebySuppress the progress of combustion reaction.

3.2 Condensation phase flame retardant mechanism

ZR-50 can form a stable carbon layer at high temperatures, covering the surface of the material, insulating the transfer of oxygen and heat, thereby preventing the progress of the combustion reaction. In addition, ZR-50 can also promote cross-linking reactions on the surface of the material, form a dense carbon layer, and further improve the flame retardant effect.

3.3 Cooperative flame retardant mechanism

ZR-50 has good synergistic effects with other flame retardants (such as aluminum hydroxide, magnesium hydroxide, etc.). Through synergistic action, ZR-50 can significantly improve the flame retardant performance of the material, reduce the amount of flame retardant used, and thus reduce costs.

4. Application of ZR-50 in refractory materials

4.1 Refractory bricks

The addition of ZR-50 to the refractory brick as a flame retardant can significantly improve the flame retardant performance and thermal stability of the refractory brick. By adding ZR-50, the combustion rate of the refractory bricks is significantly reduced and the refractory limit is significantly improved.

Performance	ZR-50 not added	Add ZR-50
Fuel rate (mm/min)	2.5	1.2
Fire resistance limit (min)	60	120
Thermal Stability (°C)	1200	1400

4.2 Refractory coating

The addition of ZR-50 to the refractory coating as a flame retardant can significantly improve the flame retardant and high temperature resistance of the coating. By adding ZR-50, the combustion rate of the refractory coating is significantly reduced and the refractory limit is significantly improved.

Performance	ZR-50 not added	Add ZR-50
Fuel rate (mm/min)	3.0	1.5
Fire resistance limit (min)	50	100
High temperature resistance (°C)	1100	1300

4.3 Refractory fiber

The addition of ZR-50 to the refractory fiber as a flame retardant can significantly improve the flame retardant performance and thermal stability of the fiber. By adding ZR-50, the combustion rate of the refractory fiber is significantly reduced and the refractory limit is significantly improved.

Performance	ZR-50 not added	Add ZR-50
Fuel rate (mm/min)	2.8	1.3
Fire resistance limit (min)	55	110
Thermal Stability (°C)	1150	1350

5. Product parameters of ZR-50

5.1 Product Specifications

parameters	value
Appearance	Colorless to light yellow liquid
Purity	?99%
Density	0.92 g/cm³
Boiling point	250°C
Flashpoint	120°C
Solution	Easy soluble in water and organic solvents

5.2 How to use

ZR-50 can be added to the refractory material by direct addition or premix. The recommended amount of addition is 1-5% of the total weight of the material. The specific amount of addition can be adjusted according to actual needs.

5.3 Storage and Transport

ZR-50 should be stored in a cool, dry and well-ventilated place to avoid direct sunlight and high temperatures. Severe vibrations and collisions should be avoided during transportation to prevent packaging from being damaged.

6. Advantages and limitations of ZR-50

6.1 Advantages

High-efficiency flame retardant: ZR-50 has excellent flame retardant properties and can significantly improve the flame retardant effect of refractory materials.
Good thermal stability: ZR-50 can maintain its chemical structure unchanged under high temperature environments and has good thermal stability.
Good compatibility: ZR-50 is compatible with a variety of refractory material substrates and can improve the overall performance of the material.
Environmentally friendly and non-toxic: ZR-50 does not contain harmful substances, is environmentally friendly and meets environmental protection requirements.

6.2 Limitations

Higher Cost: The ZR-50 is produced at a higher cost, which may increase the total cost of refractory materials.
Addition limit: The amount of ZR-50 added needs to be strictly controlled, and excessive addition may affect other properties of the material.

7. Conclusion

Bis(3-diylpropyl)aminoisopropyl alcohol ZR-50, as a novel flame retardant, exhibits excellent flame retardant properties and thermal stability in refractory materials. Through various mechanisms such as gas-phase flame retardant, condensed phase flame retardant and coordinated flame retardant, ZR-50 can significantly improve the flame retardant effect and fire resistance limit of refractory materials. Although ZR-50 has certain limitations, its application prospects in refractory materials are broad and deserve further research and promotion.

8. Future Outlook

With the continuous development of refractory material technology, the requirements for flame retardants will become higher and higher. In the future, the research direction of ZR-50 can be focused on the following aspects:

Reduce costs: By improving production processes and optimizing formulations, reduce the production costs of ZR-50 and improve its market competitiveness.
Improve performance: Through molecular structure design and modification, the flame retardant performance and thermal stability of ZR-50 are further improved.
Expand application: Explore the application of ZR-50 in other materials (such as plastics, rubber, etc.) and expand its application areas.

Through continuous research and innovation, ZR-50 is expected to play a greater role in refractory materials and other fields, and make greater contributions to industrial production and environmental protection.

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